Best placed in November. It lies south of the celestial equator and sits low for northern observers, better the further south you go.
Pyxis is centred near right ascension 8.8 hours, declination -24°. It lies south of the celestial equator and sits low for northern observers, better the further south you go.
It reaches its highest point in the sky around local midnight in November, which is when it is easiest to pick out. Earlier in the year it rises before dawn; later, it is already setting in the evening.
SkyRef draws Pyxis in its real position for wherever you are, right now, along with the other 88 IAU figures.